Recombinant Human Angiostatin (Human Angiostatin)

别名（Synonyms）

Angiostatin

Accession

P00747

GeneID

5340

表达系统（Source）

E.coli-derived HumanAngiostatin protein,Tyr98-Pro356.

分子量大小（Molecular Weight）

Approximately 29.7 KDa

氨基酸序列(AA Sequence)

VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLK GTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT TNSQVRWEYC KIPSCDSSP

标签（Tag）

None

外观（Physical Appearance）

Sterile Filtered White lyophilized (freeze-dried) powder.

纯度（Purity）

> 95% by SDS-PAGE and HPLC analyses.

生物活性（Biological Activity）

The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells in vitro and anti-angiogenesis in vivo is 5.5 × 10⁵ IU/mg. Fully biologically active when compared to standard.

内毒素（Endotoxin）

< 1 EU/μg of protein as determined by LAL method.

制剂（Formulation）

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM NaAc, pH 5.5, 4 % mannitol.

复溶（Reconstitution）

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.